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Published:
Oct 14, 2015Keywords:
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Hydrogen Bonding Patterns in a Series of 3-Spirocyclic Oxindoles
Abstract
The crystal structures of the new compounds spiro[cyclohexane-1,3’-indol] 2’(1’H)-one (1), (rel-1R,2S)-spiro[bicyclo[2.2.1] heptane-2,3’-indol] 2’(1’H)-one (2) and spiro[indole-3,2’-tricyclo[3.3.1.13,7]decan]-2(1H)-one (3) have been determined by low temperature single crystal X-ray diffraction. The effects of substitution on the hydrogen bonding pattern is compared between all three compounds.
Keywords: Hydrogen Bonding, X-ray Crystal Structure, Oxindoles, Cambridge Structural Database
