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Poly(ethylene)glycol/AlCl3 as a Green and Reusable System in the Synthesis of α,α’-bis(substituted-benzylidene) Cycloalkanones
Abstract
Aluminum chloride has been found to be a highly efficient catalyst for the aldol condensation of aldehydes and cycloketones in poly(ethylene)glycol 400 at room temperature. The reaction is very fast, clean and environmentally benign for the synthesis of a variety of α,α’-bis(substituted-benzylidene) cycloalkanones.
Keywords: Aluminum Chloride, Poly(ethylene)glycol, α,α’-bis(substituted-benzylidene) cycloalkanones, Aldol Condensation