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A Simple Three-component Synthesis of 3-Amino-5-arylpyridazine-4-carbonitriles
Abstract
New 3-amino-5-arylpyridazine-4-carbonitriles have been synthesized by a one-pot three-component reaction of malononitrile with arylglyoxals in the presence of hydrazine hydrate at room temperature in water and ethanol.
KEYWORDS Arylglyoxals, arylpyridazines, hydrazine hydrate, one-pot, malononitrile.
