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Negishi Coupling of Pteridine-O-sulfonates


W Nxumalo
A Dinsmore

Abstract

Negishi coupling of pteridine-O-sulfonate with Zn-aryls is reported. Hydrolysis of the protecting groups with 1M NH3 gave the 6-subustituted 2,4-diaminopteridine while hydrolysis with 1 M NaOH gave the 6-subsituted pterin.

KEYWORDS Pteridine, pterin, Negishi coupling.


Journal Identifiers


eISSN: 1996-840X
print ISSN: 0379-4350