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Negishi Coupling of Pteridine-O-sulfonates
Abstract
Negishi coupling of pteridine-O-sulfonate with Zn-aryls is reported. Hydrolysis of the protecting groups with 1M NH3 gave the 6-subustituted 2,4-diaminopteridine while hydrolysis with 1 M NaOH gave the 6-subsituted pterin.
KEYWORDS Pteridine, pterin, Negishi coupling.