Cavernous transformation of the portal vein a rare phenomenon

Abstract

Cavernous transformation of the portal vein is a complication of a prior portal vein thrombosis and carries a very poor prognosis. It is associated with portal hypertension, and the massive ascites that develops as a result, mimics other clinical conditions that may puzzle physicians. Elevated levels of Ca-125 is often seen in patients with associated underlying chronic liver disease, which in turn may lead to a wild goose chase for ovarian carcinoma. Portal vein thrombosis in HIV-positive patients, most likely as a result of HIV-associated thrombosis, must be considered in all HIV patients who present with features of portal hypertension and ascites.