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Published:
Jul 14, 2021Keywords:
Secondary hypertension; endocrine; pheochromocytoma; paraganglioma; screening; normetanephrines; metanephrines; succinate dehydrogenase.
Article Details
Issue
Section
Opinion (Open Forum)
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Main Article Content
Secondary hypertension: An update on the diagnosis and localisation of a pheochromocytoma or paraganglioma
Nida Siddiqui
Reyna Daya
Faheem Seedat
Saajidah Bulbulia
Zaheer Bayat
Abstract
Most cases of hypertension are because of essential hypertension, however 5% – 15% of cases can be a result of a secondary cause. In this article, we focus on the endocrine causes of secondary hypertension with a particular focus on pheochromocytomas (PCCs) and paragangliomas (PGLs). Around 15 endocrine disorders can initially present with hypertension. Amongst those PCCs and PGLs are rare but potentially life-threatening causes. An early diagnosis and timely referral can be life-saving. Herein, we present an approach for screening and diagnosis of these patients and focus on the importance of genetic testing.
