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Main Article Content
Case report: A case report of optic nerve glioma in a 5-year-old African girl
Abstract
Background: Optic nerve gliomas are rare tumors that constitute less than 5% of all pediatric central nervous system tumors.
Case Presentation: We present the case of a 5-year-old girl with complaints of progressive protrusion of the right eye and poor vision of 3 years duration who was referred to the ophthalmologist. Ophthalmological evaluation of the right eye revealed tearing, no perception of light, inferior dystopia, severe proptosis, and a firm non-tender orbital mass palpable posterior to the eyeball. The cranial CT-scan was suggestive of a right optic nerve glioma. Histology showed Optic Glioma with extensive proliferation of meningothelial cells.
Conclusion: Optic gliomas can be associated with extensive proliferation of meningothelial cells that can histologically mimic a meningioma. It is important to be cautious about making a diagnosis of meningioma for tumors in locations that are also characteristic of optic nerve gliomas especially in appropriate clinical settings.
French title: Rapport de cas : Un rapport de cas de gliome du nerf optique chez une fillette africaine de 5 ans Titre en cours - Gliome optique chez une fillette africaine
Contexte de l'étude : Les gliomes du nerf optique sont des tumeurs rares qui constituent moins de 5 % de toutes les tumeurs pédiatriques du système nerveux central.
Présentation de cas : Nous présentons le cas d'une fillette de 5 ans présentant des plaintes de protrusion progressive de l'œil droit et une mauvaise vision depuis 3 ans qui a été référée à l'ophtalmologiste. L'évaluation ophtalmologique de l'œil droit a révélé un larmoiement, une absence de perception de la lumière, une dystopie inférieure, une exophtalmie sévère et une masse orbitaire ferme et non douloureuse, palpable en arrière du globe oculaire. Le scanner crânien était évocateur d'un gliome du nerf optique droit. L'histologie montrait un gliome optique avec une prolifération étendue de cellules méningothéliales.
Conclusion : Les gliomes optiques peuvent être associés à une prolifération étendue de cellules méningothéliales pouvant mimer histologiquement un méningiome. Il est important d'être prudent avant de poser un diagnostic de méningiome pour des tumeurs situées dans des localisations également caractéristiques des gliomes du nerf optique, en particulier dans des contextes cliniques appropriés.
