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Main Article Content
Exploring atypical manifestations of Mpox: Anarrative review
Abstract
Mpox (formerly referred to as monkey pox), a viral infection known for its characteristic manifestations, presents with atypical symptoms, leading to diagnostic and management challenges. Recent outbreaks of the disease have also revealed changes in the epidemiologic patterns of the disease with many cases going unnoticed. These scenarios if not properly identified and addressed can led to increased healthcare burden created by the virus. To conduct the narrative review of the concerned literature, a comprehensive and well through search from PUBMED, Google scholar, EMBASE and African Journal Online Evaluating Studies was conducted from published works between 2003 to 2023. This narrative review aims at exploring the atypical manifestations of Mpox, by reviewing various manifestations of the disease, examining the overlying mechanisms and factors influencing these manifestations; and more so, assessing various clinical implications and challenges facing its management, with the hope of suggesting future directions in tackling the clinical implications and challenges. Regarding the atypical manifestations of Mpox, the review focused on the neurological, dermatological, and respiratory presentations, highlighting the diverse symptoms observed in each case. In addition, accurate diagnosis of atypical cases is crucial and requires a high index of suspicion, comprehensive differential diagnosis, and appropriate diagnostic testing. Tailored strategies for treatment are essential to address the specific manifestations observed. For future research, a focus on elucidating the pathogenesis, identifying risk factors, improving diagnostic approaches, and evaluating treatment strategies for atypical
French title: Mpox cases is required. Explorer les manifestations atypiques de Mpox: une revue narrative Titre fonctionnement proposé : Manifestations atypiques de Mpox
La variole du singe (anciennement appelée variole du singe), une infection virale connue pour ses manifestations caractéristiques, présente des symptômes atypiques, entraînant des défis de diagnostic et de prise en charge. Les récentes épidémies de la maladie ont également révélé des changements dans les schémas épidémiologiques de la maladie, de nombreux cas passant inaperçus. S'ils ne sont pas correctement identifiés et traités, ces scénarios peuvent entraîner une augmentation du fardeau des soins de santé créé par le virus. Pour mener l'examen narratif de la littérature concernée, une recherche complète et approfondie de PUBMED, Google Scholar, EMBASE et African Journal Online Evaluating Studies a été menée à partir d'ouvrages publiés entre 2003 et 2023. Cette revue narrative vise à explorer les manifestations atypiques de la Mpox, en passant en revue diverses manifestations de la maladie, en examinant les mécanismes sous-jacents et les facteurs influençant ces manifestations ; et plus encore, évaluer diverses implications cliniques et défis auxquels est confrontée sa gestion, dans l'espoir de suggérer des orientations futures pour aborder les implications et défis cliniques. Concernant les manifestations atypiques de Mpox, la revue s'est concentrée sur les présentations neurologiques, dermatologiques et respiratoires, mettant en évidence les divers symptômes observés dans chaque cas. En outre, un diagnostic précis des cas atypiques est crucial et nécessite un indice de suspicion élevé, un diagnostic différentiel complet et des tests diagnostiques appropriés. Des stratégies de traitement sur mesure sont essentielles pour traiter les manifestations spécifiques observées. Pour les recherches futures, il est nécessaire de se concentrer sur l'élucidation de la pathogenèse, l'identification des facteurs de risque, l'amélioration des approches diagnostiques et l'évaluation des stratégies de traitement pour les cas atypiques de Mpox.
