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Prevalence of metabolic syndrome among chronic kidney disease patients attending a tertiary hospital in Nigeria – a cross - sectional study


A.B. Olokor
O.E. Olokor

Abstract

Objective: Metabolic syndrome and chronic kidney disease are major public health challenges. This study aimed at determining the prevalence of metabolic syndrome among chronic kidney disease patients.

Methods: One hundred and sixty patients were enrolled. Glomerular filtration rates were estimated using the Cockcroft Gault formula. Metabolic syndrome was defined by the presence of ≥ 3 of the following: Central obesity (waist circumference of >102 cm in males or >88 cm in females); Hypertriglyceridemia
>150 mg/dL, low HDL cholesterol (<40 mg/Dl in males and <50 mg/dL in females), Hypertension (>130/85mmHg), Fasting plasma glucose >100 mg/dL.

Results: The overall prevalence of metabolic syndrome was 67.5%, CKD stage 5 had the highest prevalence (85.1%) (p = 0.165). Prevalence among diabetics was 82% (p <0.000). CKD stage and number of metabolic syndrome criteria positively correlated.

Conclusion: approximately seven out of every 10 CKD patients had metabolic syndrome. It was more associated with advanced CKD. Diabetics compared to non-diabetics were 1.5 times more predisposed.

Keywords: Metabolic syndrome, chronic kidney disease, diabetes mellitus


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eISSN: 2467-8252
print ISSN: 2360-7793