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Research priorities for accelerating the achievement of three 95 HIV goals in Cameroon: a consensus statement from the Cameroon HIV Research Forum (CAM-HERO)


Anastase Dzudie
Boris Tchounga
Rogers Ajeh
Charles Kouanfack
Peter Vanes Ebasone
Tatiana Djikeussi
Léonard Bonono Nyoto
Joseph Fokam
Jérôme Ateudjieu
Patrice Tchendjou
Ezechiel Ngoufack Jagni Semengue
Fabrice Youbi
Jean Anoubessi
Marie Varloteaux
Boris Youngui
Felicite Naah Tabala
Benjamin Atanga
Leonie Simo
Armel Zemsi
Emile Shu Nforbih
Gilles Ndayisaba
Annereke Nyenti
Apungwa Cornelius Ntabe
Therese Abong Bwemba
Eugene Sobngwi
Serge Billong
John Ditekemena
Anne Cecile Zoung-Kanyi Bisseck
Louis Richard Njock

Abstract

Introduction: the Treat-All remains the globally endorsed approach to attain the 95-95-95 targets and end the AIDS pandemic by 2030, but requires some country-level contextualization. In Cameroon, the specific research agenda to inform strategies for improving HIV policy was yet to be defined.


Methods: under the patronage of the Cameroon Ministry of health, researchers, policy makers, implementing partners, and clinicians from 13 institutions, used the Delphi method to arrive at a consensus of HIV research priorities. The process had five steps: 1) independent literature scan by 5 working groups; 2) review of the initial priority list; 3) appraisal of priorities list in a larger group; 4) refinement and consolidation by a consensus group; 5) rating of top research priorities.


Results: five research priorities and corresponding research approaches, resulted from the process. These include: 1) effectiveness, safety and active toxicity monitoring of new and old antiretrovirals; 2) outcomes of Antiretroviral Therapy (ART) with focus in children and adolescents; 3) impact of HIV and ART on aging and major chronic diseases; 4) ART dispensation models and impact on adherence and retention; 5) evaluations of HIV treatment and prevention programs.


Conclusion: the research priorities resulted from a consensus amongst a multidisciplinary team and were based on current data about the pandemic and science to prevent, treat, and ultimately cure HIV. These priorities highlighted critical areas of investigation with potential relevance for the country, funders, and regulatory bodies.


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eISSN: 1937-8688