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Anti-glomerular basement membrane disease with intense nephrotic syndrome: a new case report


Ikram Mami
Emna Ghzel
Rym Abida
Fadwa Hlaoui
Hela Jebali
Lamia Rais
Soumaya Beji
Fethi Ben Hamida
Lilia Ben Fatma
Karim Zouaghi

Abstract

Anti-glomerular basement membrane (anti-GBM)
disease was usually described as a small vessel
vasculitis presenting with acute kidney injury,
haematuria and non-nephrotic proteinuria. We
report a case of anti-GBM disease revealed by an
intense nephrotic syndrome. The urinary protein
level was 12g/day. Renal biopsy only showed
crescent glomerulonephritis with linear staining of
IgG in direct immunofluorescence without other
glomerulonephritis. Immunoglobulin G (IgG) antiGBM antibody titer was elevated.


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eISSN: 1937-8688