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Mucocutaneous leishmaniasis: case report and literature review of a rare endonasal infection
Abstract
Leishmaniasis is a protozoal infection transmitted
by a sandfly vector. In Germany, leishmaniasis of
the mucous membranes is a rare condition and
usually due to extension of local skin disease into
the mucosal tissue via direct extension,
bloodstream or lymphatics. We report a case of
endonasal leishmaniasis in a female German
resident who presented in a university hospital
with nasal obstruction. Histology of the left nasal
septum biopsy was suggestive of leishmaniasis.
The molecular detection of DNA was positive for
leishmania infantum. The patient was successfully
treated as a case of mucocutaneous leishmaniasis
receiving liposomal amphotericin follow up visits
showed significant improvement with no
recurrence.