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Published:
Jun 6, 2019Keywords:
Syphilis; immuno-chromatographic rapid test, false positivity; race; environment; Central Africa; France
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Differential influence of race and environment on indeterminate reactivities to non-treponemal and treponemal antigens by immunochromatographic dual syphilis rapid test
Abstract
Introduction: syphilis rapid test results may be influenced by numerous environmental and genetic factors. Methods: the proportion of false
positive syphilis non-treponemal (NT) and treponemal (T) test results using immuno-chromatographic dual syphilis rapid test on serum from
Cameroonian blacks (n=103) versus French blacks (n=104) or French caucasians (n=51), all HIV-negative and free of clinical syphilis, was examined.
Results: Black individuals in Cameroon had a significantly higher frequency of false positive NT or T tests than black individuals in France. black
individuals in France had a higher frequency of indeterminate NT tests as compare
