Multiple paraneoplastic syndromes revealing non-small cell lung carcinoma

Abstract

A broad spectrum of paraneoplastic dermatoses is associated with lung cancer. We report herein a 56-year-old man who presented an association of erythroderma, acquired ichthyosis, palmo-plantar keratoderma,  hypereosinophilia and hyper IgE. In light of these clinical and biological assessments an underlying malignancy  had been suspected. A thoracic, abdominal and pelvic computed tomography showed a left hilar mass. The patient underwent a left pneumonectomy and the  histological study had confirmed a non-small cell lung  cancer. Recognition of cutaneous paraneoplastic syndromes is important since it leads to prompt diagnosis  of an underlying malignancy and consequently a better management and prognosis of the disease.

Key words: Carcinoma, paraneoplastic dermatoses, IgE