Ovarian cancer revealed by paraneoplastic cerebellar degeneration: a case report

Abstract

The prevalence of paraneoplastic cerebellar degeneration (PCD) associated with gynecological cancer is rare. Here, we reported the first case of ovarian cancer revealed by PCD in our institute. we describe a 80- year –old  Moroccan female presented with subacute vestibular and cerebellar syndromes, she had an inguinal  lymphadenopathy,with high levels of Anti-YO. Rapid progression and absence of known etiologies point   towards a probable paraneoplastic origin of the syndrome in this patient. The exact incidence of PNS among   those diagnosed with cancer remains uncertain, it is important to report this cases in the literature to help  early diagnosis and appropriate treatment, which are able to stabilize the neurological symptoms.

Key words: Paraneoplastic cerebellar degeneration, Paraneoplastic syndromes, ovarian cancer