A cross-sectional seroepidemiological study of camel (Camelus dromedarius) brucellosis and associated risk factors in the Sultanate of Oman

Abstract

Brucellosis is a globally distributed and economically devastating zoonotic disease of multiple species, including camels. Human and livestock brucellosis is prevalent in Oman, especially in southern Dhofar governorates of Oman, where camels share habitat and have close contact with other susceptible species. We conducted a randomized crosssectional sero-epidemiological study to investigate the seroprevalence of brucellosis in camels of Oman. The sera from 2,250 camels from 552 geographically marked farms were screened through Rose Bengal plate agglutination test and later confirmed by the competitive ELISA (COMPLIZA, VLA, UK). In total, nine [0.4%, confidence interval (CI) 0.4, 0.8] camels from eight (1.5%, CI 0.6, 2.8) herds were tested positive for brucellosis. The highest prevalence was recorded in Dhofar (3.7%, CI 1.4, 7.9) and the lowest in Sharqiyah (1.3%, CI 0.0, 7.2) governorate (p = 0.052). All seropositive camels were of local breed and females. Seroprevalence was higher (0.5%, CI 0.2, 1.0) in adults (>4 yr of age) as compared with young (≤4 yr of age) camels (0.2%, CI 0.0, 0.8). The results of binary logistic regression indicated that camel herds located in south (Dhofar) [odds ratio (OR) 6.39, CI 1.01, 40.67], practice of open replacement system (OR 14.49, CI 1.83, 114.51) and with history of abortions (OR 8.01, CI 1.34, 47.77) were more likely to test positive for brucellosis. We conclude that brucellosis is endemic at a low level in camels of Oman and a control strategy based upon test-and-slaughter/inclusion of camels in the current vaccination program after carefully planned vaccine evaluation studies could be considered to control it.

Keywords: Brucellosis, Camel, Oman, Risk factors, Seroepidemiology