A rare case of pituitary chromophobe carcinoma in a dog: Clinical, tomographic and histopathological findings

Abstract

A 9 year old male mixed-breed dog was presented for progressive aggressiveness towards the owner. The neurological evaluation was consistent with a forebrain  syndrome. Magnetic Resonance Imaging (MRI) of the brain revealed enlargement of the third ventricle and presence of a large spheroidal neoplasm in the sellar/parasellar region suggestive of a pituitary macroadenoma. On the owner request, the dog was euthnized. Histopathological examination revealed the presence of a pituitary  chromophobe carcinoma. To the author’s knowledge, pituitary carcinomas have been rarely described in dogs, especially the chromophobe subtype.

Keywords: Brain, Chromophobe carcinoma, Histology, Pituitary neoplasm, Tumour.