Prediction of pregnancy outcomes based on CPR index in normal and high-risk pregnancies

Abstract

Background: The use of Doppler ultrasound has signifi cantly reduced perinatal mortality and morbidity. Color Doppler
ultrasound provides direct information about vascular resistance and indirect information about blood fl ow. The
Cerebroplacental Ratio (CPR) is a unique fetal Doppler parameter for quantifying reperfusion that can be associated with
increased placental resistance and brain sparing effect. Given the importance of this issue in reducing morbidity and
perinatal mortality, we decided to conduct a study to evaluate the CPR in predicting perinatal outcomes.
Method: In this study, 68 women with pregnancies between 30 and 36 weeks were examined for Doppler parameters. Half
of the mothers had high-risk pregnancies (case group) and half had normal pregnancies (control group). Information about
Apgar score, NICU hospitalization, the need for a ventilator, emergency cesarean section due to fetal distress, and type
of delivery were collected and then the CPR was compared between the control and case groups according to different
variables.
Results: This study showed that 10 patients in the high-risk group had CPR<1 compared to 2 patients in the low-risk group,
which was associated with poor neonatal outcomes, NICU hospitalization, and preterm delivery.
Conclusion: Abnormal CPR is associated with adverse pregnancy outcomes and can be a predictor of pregnancy outcomes
in high-risk pregnancies.