Vaccination with newcastle disease vaccines strain i2 and lasota in commercial and local chickens in Plateau State Nigeria

Abstract

Vaccination trials and comparative immunogenicity study using Newcastle disease vaccine strain I2 (NDVI2) and NDV La Sota administered to commercial and local chickens through intraocular (i/o), intramuscular (i/m), drinking water (dw), untreated sorghum, parboiled sorghum, sorghum coated with gum Arabic or commercial chick mash feed as vaccine carriers was conducted. Newcastle disease vaccine strain I2 and NDV La Sota vaccines provided protection to commercial and local chickens vaccinated through i/o, i/m or dw. No significant difference (P.0.05) was observed in the antibody titre of commercial or local chickens vaccinated with either NDVI2 or NDV La Sota vaccines administered via commercial feed, parboiled sorghum, parboiled sorghum coated with gum Arabic and untreated sorghum. NDVI2 or NDV La Sota vaccines administered through commercial feed, parboiled sorghum, parboiled sorghum coated with gum Arabic and untreated sorghum gave no or limited protection (0-22%) to the birds when challenged with a local strain of velogenic viscerotropic Newcastle disease virus Kudu 113 strain. It was concluded that the vaccine carriers used in this study were not suitable for delivery of NDVI2 or NDVS La Sota vaccines to local or commercial chickens.