Prevalence and antimicrobial resistance pattern of coagulase negative Staphylococci isolated from pigs and in-contact humans in Jos Metropolis, Nigeria

Abstract

The nasal carriage and antibiotic susceptibility pattern of coagulase negative  staphylococci (CoNS) isolates from healthy pigs and in-contact humans were  investigated in 300 pigs and 101 in-contact humans from pig farms and abattoir. The results indicate that 13.2% (53/401) of the isolates were CoNS species based on confirmatory test with Microgen biochemical kit and were further subjected to antibiotic susceptibility testing. Nine CoNS species were identified; S. haemolyticus (n = 10), S. simulans (n =5), S. chromogen (n = 9), S. warneri (n =5), S. xylosus (12), S. epidermidis (n = 5), S. schleiferi (n = 5) and S. hominis (n = 2). Overall, resistance to beta-lactams was the most observed; 79.2% of the isolates were resistant to penicillin while 11.3% and 7.5% were respectively resistant to oxacillin and cefoxitin, respectively.  Resistance to 2 or more antimicrobial agents was observed in 39.6% (21/53) of the CoNS isolates. All the isolates were resistant to at least one antimicrobial agent except for gentamicin. Multidrug resistant CoNS are common colonizers of apparently healthy pigs and in-contact humans in the study area with S. xylosus and S. haemolyticus being the major species detected.

Key words: Antibiotics, CoNS, pigs, humans.