Cystographic evaluation post colocystoplasty in two Nigerian indigenous dogs

Abstract

A study was conducted to evaluate “graft-take” in an experimentally reconstructed urinary bladder by colocystoplasty in two adult dogs. Predetermined 2x3 cm dimension of urinary bladder defect was created on the dorsum and the ventrum of the urinary bladder and was patched with harvested 3x6 cm colonic pedicle flap. All operations were humanely conducted. Urographic evaluation for graft-take was done on days 21 and 49 post colocystoplasty by infusing Urografin^(R)-76% (sodium amidotrizoate + meglumine amidotrizoate + Iodine) transurethrally. The urinary bladder architecture was preserved and maintained without obvious evidence of the grafted portion. The cystogram revealed an apparent dome-shaped with slight irregular mural thickness at day 21 which was not displayed cystographically on day 49 postoperative. This was evident of the textural difference of the colonic flap compared with the thicker urinary bladder. The healing pattern and the return to physiologic function of the reconstructed urinary bladder conclusively revealed that the colonic pedicle flaps are useful in repair of major urinary bladder defect. These flaps are suitable graft tissues.

Keywords: Urinary bladder, Colocystoplasty, Cystography, Nigerian Indigenous dogs