Morphological Pattern of Childhood Solid Tumours in Lagos University Teaching Hospital.

Abstract

Background: There is a wide variation in the incidence of childhood tumors world wide. The relative incidence of childhood tumors in developing countries is increasing and might add significantly to the high childhood morbidity and mortality caused by infectious diseases. There is need to determine the incidence of childhood cancer in different centers of the country and contribute to the National cancer register Objective: The aim of this study is to determine the burden and patterns of childhood tumour in our environment. Methods: A retrospective review of histologically diagnosed cases of childhood tumours seen from January 2000 to 2007 from the records of the department of Morbid Anatomy of the Lagos University Teaching Hospital (LUTH), Nigeria was carried out. All the cases were analyzed for age and gender distribution as well as histological types Results: Malignant tumours constituted 30.50% of the tumours of which retinoblastoma is the most common. The most common benign tumour was fibroadenoma accounting for 36.2% of all benign tumours. The female to male ratio for malignant and benign tumours are 1:1 and 1:1.3 respectively. The peak age incidence was 11 – 15 years for benign and 1 – 5 for malignant tumours. . Conclusion: The study showed decrease in the annual incidence of childhood tumours in Lagos. There was however no difference in the pattern when compared with other centers in Nigeria and in other African countries.

Keywords: Morphology, Pattern, Childhood, Solid tumours