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The reproductive dysfunction effects of gasoline inhalation in albino rats


CC Ugwoke
ED Nwobodo
P Unekwe
M Odike
ST Chukwuma
G Amilo

Abstract

Daily exposure to fuel vapour may pose significant health risk to exposed individuals. Fifteen each of male and female albino rats weighing between 110-230g were divided into test (10) and control (5) groups each. The test animals were exposed to inhalation gasoline for one hour daily for twenty-one consecutive days. All animals were then bled and the serum levels of the reproductive hormones determined. The results showed significant (P<0.05) reduction in the serum levels of all the hormones of reproduction in both the male and female test animals. The results suggest that inhalation gasoline exposure significantly (P<0.05) lowers the levels of reproductive hormones in albino rats and may thus interfere with reproduction.

Keywords: gasoline, wistar, hormones, reproduction

Nigerian Journal of Physiological Sciences Vol. 20(1&2) 2005: 54-57

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eISSN: 0794-859X