The Phytochemical, Antibacterial and Antifungal Activity of the Crude Extract of Sida Acuta (Malvaceae) Leaf

Abstract

The phytochemical constituents and anti-microbial activity of the crude extract of Sida acuta (malvaceae) leaf were investigated during the wet season. The methanolic and aqueous crude extracts of Sida acuta (malvaceae) was obtained through standard procedure. The minimal inhibitory concentration of these crude extracts were determined using five cultures of Candida albicans, Staphylococcus aureus, Escherichia coli, Salmonella coliform and Klebsiella spp. The methanolic crude extracts of Sida acuta (malvaceae) was found to be active against Staphylococcus aureus and Candida albicans with a minimal inhibitory concentration of 62.50mg/ml and 31.250mg/ml respectively. Also, the aqueous crude extract of Sida acuta (malvaceae) was found to be active against Staphylococcus aureus, Candida albicans and Escherichia coli with a minimal inhibitory concentration of 62.5mg/ml, 31.25mg/ml and 62.5mg/ml respectively. The leaves of Sida acuta (malvaceae) showed good anti-bacteria and anti-fungal activity.

Nigerian Journal of Pharmaceutical Research, Vol. 9 No 2 pp. 103 – 109 (September 2011)