Case Report: Acute disseminated encephalomyelitis in two Nigerian children with typhoid fever

Abstract

The involvement of central nervous system in children with typhoid fever is common. However, encephalopathy with focal neurological signs, coma and cerebellitis is rare. We report two children from the South-western part of Nigeria with blood culture proven typhoid fever who developed encephalopathy and acute cerebellar syndrome due to acute disseminated encephalomyelitis (ADEM). In this report, we discussed the symptomatology and management of post-Salmonella disseminated encephalomyelitis in children.