An uncommon case of noninvasive ocular surface squamous neoplasia involving the entire cornea

Abstract

Ocular surface squamous neoplasia (OSSN) is relatively rare with an incidence of 0.13–1.9/100,000 population. OSSN includes dysplastic lesions involving the squamous epithelium of the conjunctiva or cornea. Epibulbar squamous cell carcinoma and epithelioma have been noted commonly, but cases in which the tumor is primary on the cornea are sufficiently rare to warrant reporting in each instance. We describe a rare case of noninvasive OSSN involving the entire cornea in a human immunodeficiency virus‑negative patient. The patient was successfully treated with no recurrence, after intact surgical removal, mitomycin C treatment, and cryotherapy.

Keywords: Noninvasive ocular surface squamous neoplasia, ocular surface squamous neoplasia involving entire cornea, squamous cell carcinoma cornea