The Effect Of Cucumis Metuliferus E Meye (Cucurbitaceae) On Rat Gastric Functions And Mucosa Intergrity

Abstract

Extract of fruit pulp of Cucumis metuliferus was screened for its effects on gastric functions and mucosal intergrity in albino rats. The study revealed
significant (P < 0.05) dose-dependent decrease in the number and type of gastro mucosal lesions as compared to ranitidine (a standard anti-gastric ulcer drug). Similarly, the effect of the extract on gastric acid secretion was significant (P < 0.05). The results of this work showed that extract of Cucumis
metuliferus significantly reduces gastro mucosal lesions and can be use for the treatment of peptic ulcer disease.