Antimicrobial Studies On Nicandra physaloides

Abstract

Antimicrobial studies were carried out using methanolic and aqueous extract of leaf, fruit, stem and root of Nicandra physaloides. The microorganisms used in study were Bacillus subtilis NCIM 2439, Mycobacterium phelei, Proteus mirabilis and Staphylococcus edidermidis NCIM 2493, Candida albicans and Aspergilus flavus NCIM535. Penicillin for gram-positive bacteria, streptomycin for gram-negative bacteria and clotrimazole for fungi were used as standard. The Nicandra physaloides extract both methanolic and aqueous was active against gram positive and gram negative bacterial strains. Both methanolic and aqueous extract of leaves and roots was active against fungi Candida albicans and Aspergillus flavus.

Keywords: Nicandra physaloides, Solanaceae, Antimicrobial activity,

Nigerian Journal of Natural Products and Medicine Vol. 11 2007 pp. 71-74