Alireza Ghannadi
Department of Pharmacognosy, School of Pharmacy and Pharmaceutical Sciences, , Isfahan University of Medical Sciences, Isfahan 81746-73461, Iran
Seyed-Ebrahim Sajjadi
Department of Pharmacognosy, School of Pharmacy and Pharmaceutical Sciences, , Isfahan University of Medical Sciences, Isfahan 81746-73461, Iran
Daryoush Abedi
Department of Pharmaceutical Biotechnology, School of Pharmacy and Pharmaceutical Sciences, , Isfahan University of Medical Sciences, Isfahan 81746-73461, Iran
Jalilvand Yousefi
Department of Microbiology, Razi State Vaccine and Serum Research Institute, Karaj , Iran
Reza Daraei-Ardekani
Department of Pharmaceutical Biotechnology, School of Pharmacy and Pharmaceutical Sciences, , Isfahan University of Medical Sciences, Isfahan 81746-73461, Iran
Abstract
Helicobacter pylori has been implicated in the etiology of stomach cancer and ulcers. The activity of total extract and polarfraction of Iranian medicinal plants Dracocephalum moldavica, Lavandula angustifolia, Rosmarinus officinalis, Salvia officinalis, Teucrium polium, Thymus daenensis and Zataria multiflora from the Mint family were tested and evaluated for inhibitory activity against some clinical isolates of H. pylori. Among these plants, methanolic extracts of Z. multiflora, D. moldavica and polar fraction of T. daenensis,R. officinalis and L. angustifolia were found to be the most effective.
Key words: Helicobacter pylori, Lamiaceae, Dracocephalum moldavica, Lavandula angustifolia, Rosmarinus officinalis, Salvia officinalis, Teucrium polium, Thymus daenensis and Zataria multiflora, antimicrobial, Iranian plants
Nig. J. Nat. Prod. and Med. Vol.8 2004: 40-42