GO Ajayi
Department of Pharmacognosy and 1Physiology, College of Medicine, University of Lagos, PMB 12003, Lagos, Nigeria
BJ Adegunloye
Department of Pharmacognosy and 1Physiology, College of Medicine, University of Lagos, PMB 12003, Lagos, Nigeria
O Oroye
Department of Pharmacognosy and 1Physiology, College of Medicine, University of Lagos, PMB 12003, Lagos, Nigeria
Abstract
Crinum glaucum used traditionally in Western Nigeria for treatment of asthma was investigated for its effects on respiratory and cardiovascular functions. Increasing doses of the aqueous extract caused an increase in tidal volume (increase in ventilatory rate and depth) and a corresponding decrease in both systolic and diastolic pressures. This therefore supports the claim by the traditional medical practitioner that preparation from this plant is useful in the treatment of asthma.
Key Words: Crinum glaucum, Amaryllidaceae, asthma, respiratory and cardiovascular activity.
Nig. J. Nat. Prod. And Med. Vol.1 1997: 15-16