K. K. Ajibesin
Department of Pharmacognosy, University of Uyo
D, N. Bala
Department of Pharmacognosy, University of Uyo
B. A. J Ekpo
Department of Pharmacognosy, University of Uyo
S. A. Adesanya
Department of Pharmacognosy, Obafemi Awolowo University, Ile-Ife, NIGERIA
Abstract
Different parts of eight plants implicated in Akwa Ibom ethnomedicinal literature as toxic were examined for toxicity in rats after oral and intraperitoneal administration. Only the ethanolic extract of S. indica leaves was toxic by both oral and intraperitoneal routes. The extract of C. edulis roots, E. kamerunica leaves, T. occidentalis root, P. mildbreadii root and B. sapinda leaves were only toxic at various dose levels through the intraperitoneal route.
Keywords: Coula edulis, Olacaceae, Caladium bicolor, Araceae, Anchomanes difformis, Araceae, Telfairia occidentalis, Curcurbitaceae, Pterocarpus mildbraedii, Fabaceae, Stachytarpheta indica, Verbernaceae, Euphorbia kamerunica, Euphorbiaceae, Blighia sapinda, Sapindaceae, Toxicity.
[Nig. J. Nat. Prod. And Med. Vol.6 2002: 7-9]