Article Sidebar
Article Details
Issue
Section
Articles
On acceptance, the copyright of the paper will be vested in the Journal and Publisher.
Main Article Content
The frequency and pattern of cardiac autonomic neuropathy(CAN) in Type 2 DM patients in a diabetic clinic in Enugu South-east Nigeria
Abstract
STUDY OBJECTIVES: To determine the frequency, pattern and grades of cardiac autonomic neuropathy (CAN) in type 2 diabetic patients in a diabetes mellitus (DM) clinic in Enugu South-East Nigeria.
METHODS: A cross sectional study of seventy (70) type 2 diabetic patients attending a DM clinic in Enugu South-East Nigeria was carried out. Cardiac autonomic function was determined using a battery of 5 non-invasive tests which include; Heart rate response (HRR) to Valsalva manoeuvre, HRR to deep breathing, HRR to standing, Resting heart rate, and Blood pressure (BP) response to standing.
RESULTS: The frequency of cardiac autonomic neuropathy (CAN) in type 2 diabetic patients was 44.3%. Resting tachycardia was the most specific, HRR to Valsalva manoeuvre was most sensitive while BP response to standing had the best positive predictive value in detecting cardiac autonomic neuropathy.
CONCLUSIONS: Cardiac autonomic neuropathy is a common complication in type 2 Diabetes Mellitus patients seen at Enugu. It is therefore recommended that Autonomic function test should be part of the standard care of type 2 diabetic patients and appropriate management instituted for both primary and secondary prevention.
KEY WORDS: Frequency, Cardiac Autonomic Neuropathy, Diabetes mellitus, Enugu, South-East Nigeria
METHODS: A cross sectional study of seventy (70) type 2 diabetic patients attending a DM clinic in Enugu South-East Nigeria was carried out. Cardiac autonomic function was determined using a battery of 5 non-invasive tests which include; Heart rate response (HRR) to Valsalva manoeuvre, HRR to deep breathing, HRR to standing, Resting heart rate, and Blood pressure (BP) response to standing.
RESULTS: The frequency of cardiac autonomic neuropathy (CAN) in type 2 diabetic patients was 44.3%. Resting tachycardia was the most specific, HRR to Valsalva manoeuvre was most sensitive while BP response to standing had the best positive predictive value in detecting cardiac autonomic neuropathy.
CONCLUSIONS: Cardiac autonomic neuropathy is a common complication in type 2 Diabetes Mellitus patients seen at Enugu. It is therefore recommended that Autonomic function test should be part of the standard care of type 2 diabetic patients and appropriate management instituted for both primary and secondary prevention.
KEY WORDS: Frequency, Cardiac Autonomic Neuropathy, Diabetes mellitus, Enugu, South-East Nigeria
