Prostate adenocarcinoma with unilateral testicular metastasis: two cases with different presentations

Abstract

Background: Most patients with prostate cancer present with advanced disease in sub-Saharan Africa. However, metastasis to the testis is rare.
Findings: This report details the incidental detection of isolated unilateral metastasis to the testis and epididymis from the prostate on histopathologic analysis of the orchidectomy specimen in a 77-year-old man (case 1) and the finding of palpable unilateral testicular secondary from aggressive metastatic prostate cancer in a relatively younger man (47 years old) during clinical evaluation (case 2).
Conclusion: The presentation of testicular metastasis from prostate cancer varies with the patient. A high index of suspicion in the phases of evaluation of these patients is required in order to prevent missed diagnosis.

Keywords: Prostate cancer, testicular metastasis, orchidectomy.