Antibiogram of Klebsiella Pneumoniae urinary isolates of apparently healthy individuals in Osogbo Metropolis, Nigeria

Abstract

One thousand (1,000) urine samples from apparently healthy subjects were cultured for Klebsiella pneumoniae and its antibiotic susceptibility profile to commonly used antimicrobial drugs was determined. The study was conducted in two randomly selected local government areas within Osogbo metropolis. The occurrence rate of Klebsiella pneumoniae was 38 (3.8%) and isolate were highly resistant to Tetracycline (92.1%), Amoxyllin (76.3%) and Co-trimoxazole (71.9%). Resistance to gentamicin was moderate (63.2%) while Ofloxacin, nitrofurantoin, ciprofloxacin, nalidixic acid and pefloxacin were very effective with 92.1%, 84.2%, 78.9% and 76.3% respectively sensitive to it and Cephalexin (57.9%) was moderately sensitive. More females {55.3%} than males (44.7%} had the highest infection rate and the difference was statistically significant (P<0.05).

Keywords: apparently healthy, urine, Klebsiella pneumoniae, antimicrobial agent

Nigerian Journal of Health and Biomedical Sciences Vol. 5(1) 2006: 60-63