O. S. OLADIMEJI
Department of Biochemistry, College of Medicine, University of Lagos, P.M.B 12003, Lagos, Nigeria
O. A. MAGBAGBEOLA
Department of Biochemistry, College of Medicine, University of Lagos, P.M.B 12003, Lagos, Nigeria
S. S. PETER
Department of Biochemistry, College of Medicine, University of Lagos, P.M.B 12003, Lagos, Nigeria.
T. A. ADEWOLE
National Institute of Medicine Research, Yaba, Lagos, Nigeria
I. A. AKINWANDE
Department of Biochemistry, College of Medicine, University of Lagos, P.M.B 12003, Lagos, Nigeria.
Abstract
This study was conducted to examine if there is a relationship between serum lipid and vitamin E levels and unexplained infertility and recurrent miscarriages. Eighty-two (82) healthy Nigerian Women volunteers were recruited for this study. The mean serum cholesterol and triglyceride were slightly higher in the women with unexplained infertility and recurrent miscarriage (177.50 ± 27.80 and 187.54 ± 20.92 mg/l00ml respectively) than the mean value in the fertile women (control) (155.13 ± 32.31 and 162.76 ± 24.70 mg/100ml) respectively. The difference between the sub group were however not statistically significant using the Student t- test. The serum triglycerides concentration in the primary infertility group was (188.88 ± 21.19mg/l00ml} while that of secondary infertility was (185.34 ± 23.77mg/l00ml) and that of recurrent miscarriage was 188.41 ± 17.81mg/l00ml. The difference between these sub groups were of no statistical significance. Mean serum vitamin E concentration in the fertile women (10.36 ± 3.52mg/ml) was found to be insignificantly higher than the observed values in the women with cases of unexplained infertility and recurrent miscarriage (8.97 ± 3.56mg/ml). It was concluded from this study that there is no relationship between recurrent miscarriages and unexplained infertility and the serum lipids and vitamin E levels.
KEY WORDS: Serum, Vitamin E, Cholesterol, Triglyceride, Infertility, Recurrent Miscarriage
[Nig. Jnl Health & Biomedical Sciences Vol.1(2) 2002: 71-75]