Sclerosing cholangitis with ulcerative colitis in a Nigerian woman

Abstract

Primary Sclerosing Cholangitis (PSC) is a relatively rare cause of chronic liver disease worldwide. It presents as chronic cholestasis associated with jaundice and pruritus. We report a middle aged Nigerian woman who presented with cholestatic jaundice and diagnosed with PSC with concurrent ulcerative colitis based on the characteristic CT imaging and histological findings of hepatic and colonic biopsies. To the best of our knowledge, this is the first report of PSC in Nigeria and highlights the importance of percutaneous liver biopsy and abdominal CT imaging in the diagnosis of chronic liver diseases.

Keywords: Sclerosing cholangitis, Nigeria, cholestasis, diarrhea