Antimicrobial efficacy of non-fluoride toothpaste on isolated oral microbes – An in vitro study

Abstract

Objective: To evaluate the Antimicrobial Efficacy of Non-Fluoride Toothpaste on Isolated Oral Microbes

Method: The antimicrobial activity of the non-fluoride toothpaste against isolated oral microbes was determined by dilution method at neat dilution, 1/2, 1/4, 1/8 and 1/16.

Results: Study results showed that Streptococcus spp was resistant while the maximum zone of inhibition was on Lactobacilli spp. It was also observed that zone of inhibition decreases with the increase in dilution except for Streptococcus spp.

Conclusion: This study revealed that while the non-fluoride toothpaste containing mainly triclosan and natural extract was significantly effective against most isolated oral microbes causing oral diseases it however, showed little or no effect against Streptococcus spp which is primarily involved in caries initiation.