Chemical composition from the leaf extracts of Momordica angustisepala with its antibacterial, antifungal and antioxidant activities

Abstract

The chemical constituents of weighed, air-dried leaf samples of Momordica angustisepala were examined. The bioactivity of hexane, ethyl acetate and methanol extracts of the two plants were tested against ten (10) strains of bacteria and fungi, and their antioxidant activities were studied. The GC-MS characterisation of n-hexane extract of Momordica angustisepala leaves revealed twenty-one (21) chemical compounds with n-tetracontane being the most abundant constituent with 13.86%. Ethyl acetate extract of the plant showed a total of nineteen (19) compounds with n-hexadecanoic acid (18.63 %) being the most abundant constituent of the extract. The characterisation of the methanol extract of Momordica angustisepala leaves gave thirty-two (32) compounds with clionasterol, eremophila-1(10), 11-diene and α-amyrinas principal constituent with 19.45 % each in the extract.

Keywords: Antioxidant activity, hexadecanoic acid, GC-MS