Blood glucose and body weight control of diabetic rats co-treated with micronutrients

Abstract

Disturbance in blood glucose and fuel metabolism are hallmarks of diabetes mellitus, and antioxidants are believed to play role in controlling these alterations. In the present study, manganese (10 mg/kg body weight), copper (2 mg/kg body weight) and zinc (15 mg/kg body weight) were supplemented in alloxan-induced diabetic rats for a period of 28 days. There was statistically significant (p<0.05) decrease in the final fasting blood glucose concentration of supplemented and non-supplemented groups. In addition, there was statistically significant (p<0.05) increase between the final body weight of supplemented and non-supplemented rats In conclusion, supplementation with antioxidant micronutrients might improve blood glucose control and body wastages usually experienced in diabetics.