Aphrodisiac effect of aqueous stem bark extract ofFicus sycomorus on female wistar rats

Abstract

In the present study, the effect of aqueous stem bark extract of Ficus sycomorus was evaluated on female sex hormones and sexual behavior in female Wistar rats. Adult female rats having regular estrous cycle confirmed by daily cytology of the vaginal smear analysis were used. Rats were  randomly divided into 3 groups (n=10): Group I served as a control; while group II, and III received 40 mg/kg and 80 mg/kg of the extracts  respectively. The results revealed significant increase (p<0.5) in serum concentration of the estradiol in group II and a significant decrease (p<0.5) in serum concentration of estradiol in group III in comparison with the control. There was also significant decrease (p<0.5) in serum level of progesterone in group II and no significant effect in group III in comparison with the control. The result also indicated no significant effect (p>0.5) of the extract on female sexual behavior, which may suggest no scientific basis for the use of the extract as an aphrodisiac in females.

Keywords: Ficus sycomorus, Aphrodisiac, Estradiol, Progesterone, Lordosis quotient