Phytochemical, Anticancer and Antioxidant Evaluation of Potential Chemical Consituents of Calliandria Surinamensis

Abstract

Some chemical constituents (β-Sitosterol, β-Sitosterol glucoside, β-amyrin, xanthone glycoside , and a flavanol glycoside) previously isolated and characterized from the stem bark of Calliandria surinamensis were subjected to in vitro free radical scavenging and anticancer activities using DPPH free radical scavenging method and lung cancer cell lines. Evaluation of the antioxidant and anticancer activities of the compounds revealed significant in-vitro antioxidant activity of the flavanol and xanthone glycosides. The xantone glycoside was active on the cancer cell line used for the study. The work reports for the first time the in-vitro antioxidant and anticancer profile of the isolated chemical compounds from the medicinal plant.

Key words: anticancer, antioxidant, C. surinamensis, phytochemical investigation, plant extract