Serological Investigation And Interpreting Serum Chemistry Profile Of Natural Infected Cattle By Foot And Mouth Disease

Abstract

During last outbreak of foot and mouth disease (FMD) january 2006 in Egypt. A total of 320 serum samples from infected cattle in breed farms belongs to Fayoum, EL Behera, Monofia, GHarbea and Giza governorares were examined for detection of antibodies against FMDV serotypes by liquid phase Blocking Immunoassy. From the above number of samples 20 serum samples only are used as infected group and 20 serum samples from clinically healthy animals considered as control group. Serum samples were used to establish the concentration of total protein, albumin, glucose, total cholesterol, calcium and phosphorus. Serum nitrate evaluated as indicator to nitric oxide. The results pointing that FMD was highly incidence of a new exotic strain of FMD strain A. Biochemical results showed significant decrease in total protein, albumin, total cholesterol, calcium and phosphorus in the infected group than control group, on the other hand there was a highly significant increase in serum glucose concentration of infected group. The concentration of serum nitrate was significantly increase in FMD group, suggesting that Apthovirus induce the production of nitric oxide in vivo.

New Egyptian Journal of Microbiology Vol. 17 (2) 2007: pp. 95-104