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ANTIBACTERIAL ACTIVITY OF Solenostemon rotundifolius LEAF EXTRACT AGAINST SOME PATHOGENS ASSOCIATED WITH FOOD
Abstract
Food-borne diseases by bacterial contamination are major public health problems in Nigeria, especially by
multidrug-resistant bacteria which could result in an increasingly growing problem of antimicrobial
resistance. Therefore, there is need to find potentially effective, safer and natural antimicrobial alternatives
against food poisoning bacteria. The antimicrobial activity of Solenostemon rotundifolius leaf extract was
investigated against three Gram-negative pathogenic bacteria; Escherichia coli, Salmonella typhi and
Pseudomonas aeruginosa, two Gram-positive bacteria strains: Enterococus fecalis and Staphylococcus
aureus. The antibacterial activity was evaluated by agar diffusion, minimum inhibition and bactericidal
concentration methods. Results showed that S. rotundifolius leaf extract exhibited antimicrobial activity
against both the gram-negative and gram-positive bacteria. The minimum inhibitory concentration of
microbial growth ranged from 12.5 mg/ml to 50 mg/ml against the bacteria.
