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Mar 25, 2024Keywords:
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Molecular biological studies on the effect of green tea on obese rats
Abstract
The current study was conducted on 70 male albino rats for elucidation the role of different green tea either local (E) or imported (C) and capsulated like green tea (CAP) as well as two common active principle Epigallocatechin gallate (EPI) and polyphenols (POL) on high fat ration (HFR) fed rats. The results showed that EPI and POL were showing a significant improvement in lipid profile and anti-oxidant status of rats. Meanwhile, EPI and CAP groups revealed the highest improvement in kidney function, while the Egyptian, Chinese green tea leaves and POL groups showed a significant enhancement in hepato-billiary system. All the studied groups revealed a significant improvement in cardiac function. Moreover, MEST relative expression increased in HFR group and showed a significant down-regulation in all green tea groups but EPI revealed the lowest relative expression in MEST which suggested its effect on improving obesity in rats.
