The effect of Liveria® on some hematological and biochemical parameters of treated buffalo calves

Abstract

The effect of intramuscular injection of Liveria® at a dose of 1ml/20kg body weight on hematological and biochemical parameters was investigated in fifteen apparently healthy buffalo calves of our local breed, 2-3 months age old, with average body weight 53-72 Kg in especial farm at Dakahlia Governorate. Buffalo were divided into three groups, each group five animals. The first group was injected with saline I/M (1ml/20kg) and lefted without any drug (the controlled animals). The second group was injected intramuscular by Liveria® (1ml/20 kg body weight). The third group was injected three successive intramuscular doses by Liveria (1ml/20 kg body weight) for three days. Hematological (RBCs- WBCs-Hb), biochemical aspects (total protein- albumin- globulin- serum: ALT, AST and ALP) and some minerals concentration (Ca, P and Na) were evaluated. The results showed that the administration of Liveria in calves caused a significant decrease in total erythrocytic count, haemoglobin concentration, total leukocytic count, total protein, albumin and serum AST with a significant increase also in serum calcium and inorganic phosphorus. Moreover, no changes in ALT, ALP activities and globulin level. Therefore, it was concluded that a single dose of Liveria® at dose rate (1ml /20 kg body weight) induced a significant improvement in some heamatological and biochemical parameters of treated calves.