Pharmacological studies of Pediococcus on performance and some hematological and biochemical parameters in cattle

Abstract

The use of Pediococcus (23×10⁶ CFU/calf/day) orally in drinking milk once daily for one month in Holstein calves have highly significant effect on blood picture ,liver function tests, kidney function test ,blood electrolytes and body weight in cow calves. There were a significant increase in total erythrocytes count , hemoglobin content, packed cell volume, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, thrombocyte count, total leucocytes count, neutrophils counts, eosinophil, basophils, total protein and its fractions, level of alkaline phosphatase (ALP),level of sodium ,calcium ,phosphorus and body weight . On the other hand there were significant decrease in urea and potassium level in groups treated by Pediococcus compared to the control groups. Moreover there were a non-significant changes in lymphocytes, monocytes, creatinine, alanine transaminase (ALT), aspartate transaminase (AST), in the same groups compared to the control groups.