Clinico-epidemiological profile of skin cancer in South Western Nigeria

Abstract

Background
Skin cancer is one of the most common forms of cancer. The incidence of skin cancer is on the increase among Caucasians and Africans, though there are significant differences in the pattern of presentation. This study sought to evaluate the pattern of skin cancer presentation in Ibadan, south-west Nigeria. The objective of the study was to determine the risk factors and pattern of presentation.
Methods
Data extraction forms were used to obtain information from the hospital records of patients with histological diagnoses of skin cancer between January 2001 and December 2010. The study took place at the Radiation Oncology Department, University College Hospital, Ibadan, Nigeria.
Results
A total of 126 cases were identified. The age range of patients was from 7 to 98 years, with a mean age of 46.6 years. The male-to-female ratio was 1.5:1. The peak age of incidence was between 40 and 49 years old. Of the risk factors, trauma (18.3%) and albinism (15.9%) were the most common. Squamous cell carcinoma (63%) was the most common histological sub-type recorded. The majority of the respondents presented with locally advanced (43.7%) and metastatic (22.2%) stages. The lower limb (59.9%) and head and neck region (22.0%) were the most commonly affected sites. The lungs (46.4%) were the most common site of distant metastases, followed by the liver (21.4%), and the brain (7.1%) was the least common site of metastasis.
Conclusion
The finding that majority of the respondents in this study presented with locally advanced and metastatic disease buttresses the need for public awareness programs to ensure uptake of preventive measures by the populace and emphasizes the need for early presentation.