Clinical features and the factors associated with poor outcome of measles patients at Queen Elizabeth Central Hospital

Abstract

In the twelve month period from March 1992 to February 1993. 266 consecutive children with measles were admitted to the children's unit at Queen Elizabeth Central Hospital (QECH). Blantyre. During the 12 month period the overall mortality was 10.9%; mortality was highest (22.5%) in children 12-23 months age. One-third of the children admitted were under 9 months of age. not eligible for measles vaccination. Pneumonia complicated illness of 30% of cases and was the greatest clinical predictor of mortality. Among infants under 9 months of age, who were receiving inappropriate food supplementation before 4 months of age the risk of death was 6.4 times the risk of death in children who were not receiving food supplementation. Other aspects of measles epidemiology are discussed.