Periodontal health in end-stage renal disease patients undergoing hemodialysis

Abstract

Aim: The aim of this study is to evaluate periodontal health status of the hemodialysis patients and to examine thenrelation between Russell periodontal index (RPI) and laboratory and inflammatory markers and nutritional status in thisngroup of patients.

Patients and methods: A cross-sectional study was conducted on a group of patients (n ¼ 43, mean age ¼ 51.4 ± 14.9 years) recruited nfrom the Mansoura University Nephrology and Dialysis Unit. Periodontal examination was performed using RPI. Various laboratory and ninflammatory markers were recorded, including routine biochemical and hematological data as well as serum parathyroid hormone, nferritin, and highly sensitive C-reactive protein; and nutritional status was evaluated using malnutrition inflammation score.

Results: Periodontitis was frequent in the studied patients where the mean RPI was 3.12 ± 1.55. There was a statistically significant positive association between periodontitis and patients’ ages (P ¼ 0.006). Furthermore, a significant positive association between periodontitis and BMI was detected (P ¼ 0.006), but not with serum levels of high sensitive Creactive protein (P ¼ 0.32) neither with malnutrition inflammation score (P ¼ 0.17). No relation was found between periodontitis and the different laboratory parameters such as calcium,  phosphorus, and parathyroid hormone.

Conclusion: Periodontitis is highly prevalent in hemodialysis patients, especially in older  patients, and more severe in obese individuals but not related to markers of inflammation or malnutrition.