Article Sidebar
Article Details
The Momona Ethiopian Journal of Science accepts the manuscripts for consideration with the understanding that the manuscript has not been published and is not under consideration for publication elsewhere. Only original articles will be considered for publication if they have been published previously as abstracts, but not if they have been published previously as extended abstract (>1000 words). This applies to both electronic and print versions of the journal. The authors should assign copyright ownership to the Editorial Office of MEJS in the event that the manuscript is accepted for publication in the Momona Ethiopian Journal of Science. All accepted manuscripts must be accompanied by a copyright statement signed by all authors. A copy of the copyright form will be supplied along with the final reviewed version of the manuscript that is sent for final proof- reading. Authors may make multiple copies of the form if necessary and send to the Editorial Office with author’s signature(s) even individually.
All articles published by Momona Ethiopian Journal of Science (MEJS) are Open Access under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0). Under this license, authors retain ownership of the copyright for their content, and anyone can copy, distribute, or reuse articles as long as the author and original source are properly cited. In all these cases for re-use, the authors will be given proper credit to the original publication in MEJS.
Main Article Content
Invitro Antibacterial Screening of Extracts from Selected Ethiopian Medicinal Plants
Abstract
Indigenous knowledge, literature reports and ethnobotanical records suggest that plants are the basis for medicines. They constitute natural source of antimicrobial drugs that will provide novel or lead compounds for the fight against disease. In this study, the antimicrobial activity of three selected Ethiopian medicinal plants was studied with the objective of screening their antibacterial activity. The fruits of Measalanceolata, aerial part of Cissus quadrangularis and leaf of Dodonae angustifolia were collected, air dried under shed, powdered and soaked in 80% methanol and extracted. In vitro antibacterial activity of the extracts was tested at different concentrations by using agar disc diffusion method and measuring the zone of inhibition. The plant extracts showed broad spectrum activity against gram positive (S. aureus) as well as gram negative (E. coli) bacteria, except Cissus quadrangularis which did not show any activity against E. coli. Furthermore, the plant extracts had also concentration dependant zone of inhibition against the tested bacteria. In fact, the highest activity was obtained for Dodonae angustifolia at 1000mg/ml against S. aureus. The activities are attributed to the presence of some secondary metabolites present in the tested plants which have been associated with antibacterial activities. This finding suggests that these medicinal plants can be potential source to isolate antibacterial drugs.
Keywords: Antibacterial activity, Disc diffusion, E. coli, Plant extract and S. aureus.
